Phospho-5-LO (S272) Polyclonal Antibody, 100ul Cryopreservation The protein encoded by this

The protein encoded by this gene is a member of the Mastermind-like family of proteins

In mice| expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis

Family members are well conserved in their genomic (number and size of exons) and protein (aa length among species) structures yet have markedly different tissue expression patterns

which modifies various nuclear proteins by poly(ADP-ribosyl)ation

Phospho-5-LO (S272) Polyclonal Antibody, 100ul Cryopreservation The protein encoded by thisALOX5 encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The arachidonate 5 lipoxygenasen, which is expressed specifically in bone marrow derived cells, catalyzes the conversion of arachidonic acid to 5(S) hydroperoxy 6 trans 8,11,14 cis eicosatetraenoic acid, and further to the allylic epoxide 5(S) trans 7,9 trans 11,14 cis eicosatetrenoic acid (leukotriene A4). Leukotrienes