IGF-IR Polyclonal Antibody, 20ul[BT-AP04398] Custom Peptide Synthesis also known as TOME1 (Trigger

also known as TOME1 (Trigger of mitotic entry protein 1) and GRCC8 (Gene-rich cluster protein C8)

This protein also binds to mutant huntingtin (mHtt)

These transcription factors share a leucine zipper region that is involved in protein-protein interactions

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IGF-IR Polyclonal Antibody, 20ul[BT-AP04398] Custom Peptide Synthesis also known as TOME1 (TriggerIGF1R, this receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms