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CD152 Polyclonal Antibody, 50ul Drug Development and Evaluation Members of this protein family

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CD152 Polyclonal Antibody, 50ul Drug Development and Evaluation Members of this protein familyThis gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in

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Description

Members of this protein family have an affinity for beta-galactosides

Mutations in this gene result in autosomal recessive spastic paraplegia

This protein may also play a neuroprotective role during ischemic brain injury

A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5

CD152 Polyclonal Antibody, 50ul Drug Development and Evaluation Members of this protein familyThis gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in

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