PI 3-Kinase p110Delta Polyclonal Antibody, 50ul Endonucleases & Exonucleases Mannan binding lectin serine peptidase

Mannan binding lectin serine peptidase 1 is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease

11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia

It activates the urokinase-type plasminogen activator

This gene may be associated with many disease states

PI 3-Kinase p110Delta Polyclonal Antibody, 50ul Endonucleases & Exonucleases Mannan binding lectin serine peptidasePhosphoinositide 3 kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I PI3K found primarily in leukocytes. Like other class I PI3Ks (p110 alpha p110 beta, and p110 gamma), the encoded protein binds p85 adapter proteins and GTP bound RAS. However, unlike the other class I PI3Ks, this protein phosphorylates itself, not p85 protein.