FKB1A Polyclonal Antibody, 100ul Immunology while binding to the LCK

while binding to the LCK SH2 domain occurs only upon TCR stimulation

subcellular location:Distributed throughout the cytoplasm and also localizes to the perinuclear region of both human erythroleukemia (HEL) cells and Jurkat cells

The encoded protein is highly similar to the largest subunit of the Drosophila NURF (nucleosome remodeling factor) complex

Huntington's disease and temporal lobe epilepsy

FKB1A Polyclonal Antibody, 100ul Immunology while binding to the LCKThe protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF beta receptor. It also interacts with multiple intracellular calcium