KANK2 Polyclonal Antibody, 100ul Cytokines Caspases exist as inactive proenzymes

Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits

and may represent a marker to monitor melanomic activity

|disease:A chromosomal aberration involving NFKB2 is found in a cutaneous T-cell leukemia (C-TCL) cell line

Its expression is up-regulated by estrogens and progestins

KANK2 Polyclonal Antibody, 100ul Cytokines Caspases exist as inactive proenzymesKANK2 encodes a member of the KN motif and ankyrin repeat domains (KANK) family of proteins, which play a role in cytoskeletal formation by regulating actin polymerization. The encoded protein functions in the sequestration of steroid receptor coactivators and possibly other proteins. Mutations in this gene are associated with impaired kidney podocyte function and nephrotic syndrome, and keratoderma and woolly hair.