MDC1(Phospho Ser513) Polyclonal Antibody, 50ul DNA Libraries Synthesis Expression is highest in the

Expression is highest in the cortex

it may play a pivotal role in forebrain function

H3 Lys-9 trimethylation is also required to direct DNA methylation at pericentric repeats

Alternatively spliced transcript variants encoding distinct isoforms have been reported

MDC1(Phospho Ser513) Polyclonal Antibody, 50ul DNA Libraries Synthesis Expression is highest in theThe protein encoded by this gene contains an N terminal forkhead domain, two BRCA1 C terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41 amino acid sequence. The encoded protein is required to activate the intra S phase and G2 M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double strand breaks through its BRCT motifs, and