Mouse Dickkopf Related Protein 2, DKK2 ELISA Kit, 96T Enzymes resulting from intergenic splicing between

resulting from intergenic splicing between P2RY11 and an immediately upstream gene (PPAN

Directly involved in heterochromatin formation by maintaining overall chromatin structure and| in particular| that of constitutive heterochromatin by stabilizing histone methylation

a protein kinase domain

These family members contain multiple N-terminal leucine-rich repeats| in addition to a C-terminal calponin homology domain| a type of domain that mediates interactions with actin filaments

Mouse Dickkopf Related Protein 2, DKK2 ELISA Kit, 96T Enzymes resulting from intergenic splicing betweenAntagonizes canonical Wnt signaling by inhibiting LRP5 6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5 6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone