MARH7 Polyclonal Antibody, 20ul Antibody Humanization This gene is highly expressed

This gene is highly expressed in organs involved in lipid metabolism| and may play a role in Zellweger syndrome| in which cells are deficient in peroxisomes and have impaired bile acid synthesis

Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described

Mutations and alternative splicing in TSG101 occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression

which include cyclin A

MARH7 Polyclonal Antibody, 20ul Antibody Humanization This gene is highly expressedMARCH7 is a member of the MARCH family of membrane bound E3 ubiquitin ligases (EC 6. 3. 2. 19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments (Bartee et al., 2004