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ERBeta Polyclonal Antibody, 100ul[BT-AP03081] Gene Editing The product of this gene

SKU: 84168011368

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ERBeta Polyclonal Antibody, 100ul[BT-AP03081] Gene Editing The product of this geneESR2 encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N terminal DNA binding domain and C terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta estradiol or related ligands, the encoded protein forms homo or hetero dimers that interact with specific DNA sequences to activate transcription. Some

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Description

The product of this gene belongs to the CRE (cAMP response element)-binding protein family

The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage

Contains 2 cyclic nucleotide-binding domains

The gene product has been identified as a tumor suppressor in gastric (PMID: 21602894

ERBeta Polyclonal Antibody, 100ul[BT-AP03081] Gene Editing The product of this geneESR2 encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N terminal DNA binding domain and C terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta estradiol or related ligands, the encoded protein forms homo or hetero dimers that interact with specific DNA sequences to activate transcription. Some

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