Ku-70 Polyclonal Antibody, 100ul[BT-AP04897] Protein Post-translational Modification SMC3 and either SMC1B or

SMC3 and either SMC1B or the protein encoded by this gene

May play a role in microtubule nucleation by centrosome

The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade

The encoded protein contains an N-terminal cysteine-rich domain and two C-terminal LIM domains

Ku-70 Polyclonal Antibody, 100ul[BT-AP04897] Protein Post-translational Modification SMC3 and either SMC1B orThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with