MICB Polyclonal Antibody, 20ul 3D Culture Mutations in this gene have

Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification

GO annotations related to this gene include DNA-directed RNA polymerase activity and RNA polymerase I transcription factor binding

subunit:Transcription repression requires formation of a complex with a corepressor protein of the Groucho/TLE family

it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm

MICB Polyclonal Antibody, 20ul 3D Culture Mutations in this gene haveThis gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress induced and is similar to MHC class I molecules; however, it does not associate with beta 2 microglobulin or bind peptides. Alternative splicing results in multiple