FXL12 Rabbit Polyclonal Antibody, 50ul Enzyme-Linked Immunosorbent Assay (ELISA) Notch 2 functions as a

Notch 2 functions as a receptor for membrane bound ligands

and a corresponding pseudogene has been found on chromosome 22

Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling| both in mature T-cells and during their development

The encoded protein is one of at least four similar proteins that have been found

FXL12 Rabbit Polyclonal Antibody, 50ul Enzyme-Linked Immunosorbent Assay (ELISA) Notch 2 functions as aMembers of the F box protein family such as FBXL12 are characterized by an approximately 40 amino acid F box motif. SCF complexes formed by SKP1 (MIM 601434) cullin (see CUL1; MIM 603134) and F box proteins act as protein ubiquitin ligases. F box proteins interact with SKP1 through the F box and they interact with ubiquitination targets through other protein interaction domains (Jin et al. 2004