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Human Atp-binding Cassette Sub-family G Member 5, ABCG5 ELISA Kit, 96T Human Genome Knockout Libraries [Spinorphin]: functions as an endogenous

SKU: 83074541853

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SEK211.00 SEK233.00

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Human Atp-binding Cassette Sub-family G Member 5, ABCG5 ELISA Kit, 96T Human Genome Knockout Libraries [Spinorphin]: functions as an endogenousABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+) and ATP dependent sterol transport across the cell membrane (PubMed: 27144356). Plays an essential role in the selective transport of dietary plant sterols and cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (PubMed: 11099417, PubMed: 11138003, PubMed: 27144356, PubMed: 15054092). Required for normal sterol homeostasis (PubMed:

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Description

[Spinorphin]: functions as an endogenous inhibitor of enkephalin-degrading enzymes such as DPP3

by enhancing their ligand affinity via conformational change (PubMed: 23193172)

the first step in fatty acid metabolism (PubMed: 10434065

including SMAD1 and POU4F1/Brn3a and probably NK homeodomain transcription factors

Human Atp-binding Cassette Sub-family G Member 5, ABCG5 ELISA Kit, 96T Human Genome Knockout Libraries [Spinorphin]: functions as an endogenousABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+) and ATP dependent sterol transport across the cell membrane (PubMed: 27144356). Plays an essential role in the selective transport of dietary plant sterols and cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (PubMed: 11099417, PubMed: 11138003, PubMed: 27144356, PubMed: 15054092). Required for normal sterol homeostasis (PubMed:

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