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Human Vascular Endothelial Cell Growth Factor A, VEGF-A ELISA Kit , 96T Molecular Sciences Alpha-A and alpha-B gene products

SKU: 82823700181

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Human Vascular Endothelial Cell Growth Factor A, VEGF-A ELISA Kit , 96T Molecular Sciences Alpha-A and alpha-B gene productsGrowth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1 VEGFR1 and KDR VEGFR2 receptors, heparan sulfate and heparin. NRP1 Neuropilin 1 binds isoforms VEGF 165 and VEGF 145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate

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Description

Alpha-A and alpha-B gene products are differentially expressed

May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane

CASP8 cleaves this encoded protein

The major encoded protein product

Human Vascular Endothelial Cell Growth Factor A, VEGF-A ELISA Kit , 96T Molecular Sciences Alpha-A and alpha-B gene productsGrowth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1 VEGFR1 and KDR VEGFR2 receptors, heparan sulfate and heparin. NRP1 Neuropilin 1 binds isoforms VEGF 165 and VEGF 145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate

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