Stat2 (Acetyl Lys384) Rabbit Polyclonal Antibody, 20ul Buffers & Solutions Activating transcription factor 2 may

Activating transcription factor 2 may also be involved in cell's DNA damage response independent of its role in transcriptional regulation

a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex

and being expressed in vascular endothelium cells and binding to L-selectin

The protein encoded by this gene is one of several related ligands of the KLRK1/NKG2D receptor

Stat2 (Acetyl Lys384) Rabbit Polyclonal Antibody, 20ul Buffers & Solutions Activating transcription factor 2 maySignal transducer and activator of transcription that mediates signaling by type I IFNs (IFN alpha and IFN beta). Following type I IFN binding to cell surface receptors Jak kinases (TYK2 and JAK1) are activated leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize associate with ISGF3G IRF 9 to form a complex termed ISGF3 transcription factor that enters the nucleus. ISGF3 binds to the IFN stimulated response