TNNC1 Rabbit Polyclonal Antibody, 50ul Immunology ATP6V1C2 encodes alternate transcriptional splice

ATP6V1C2 encodes alternate transcriptional splice variants

The encoded protein is essential for autophagosome formation and mitophagy

The encoded protein lacks the protein destabilizing (PEST) sequence that is present in other family members

The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor

TNNC1 Rabbit Polyclonal Antibody, 50ul Immunology ATP6V1C2 encodes alternate transcriptional spliceTroponin is a central regulatory protein of striated muscle contraction and together with tropomyosin is located on the actin filament. Troponin consists of 3 subunits: TnI which is the inhibitor of actomyosin ATPase; TnT which contains the binding site for tropomyosin; and TnC the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI thus allowing the interaction of actin with myosin the hydrolysis of ATP