JAK3 Polyclonal Antibody, 100ul Glassware The encoded protein plays a

The encoded protein plays a role in the early secretory pathway as a heterodimer with zinc transporter 6| and may also regulate zinc sequestration into secretory granules of pancreatic beta cells

200 residues at the N-terminus (domains IV

TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins

JAK3 Polyclonal Antibody, 100ul Glassware The encoded protein plays aThe protein encoded by JAK3 is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).