HERC3 Rabbit Polyclonal Antibody, 20ul Drug Development and Evaluation |Belongs to the Sp1 C2H2-type

|Belongs to the Sp1 C2H2-type zinc-finger protein family

The encoded protein shares 100% sequence identity with the mouse and rat counterparts

Mutations in this gene are associated with autosomal dominant progressive external ophthalmoplegia-6 (PEOA6) and Seckel syndrome 8

CSS3 is a glycosyltransferase that has both glucuronyltransferase and N-acetylgalactosaminyltransferase activities (Yada et al

HERC3 Rabbit Polyclonal Antibody, 20ul Drug Development and Evaluation |Belongs to the Sp1 C2H2-typeThis gene encodes a member the HERC ubiquitin ligase family. The encoded protein is located in the cytosol and binds ubiquitin via a HECT domain. Mutations in this gene have been associated with colorectal and gastric carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.