Tuberin(Phospho Ser939) Polyclonal Antibody, 50ul Bottle-Top Dispenser This gene is part of

This gene is part of a cluster of MMP genes on chromosome 11

but it may play a role in mRNA processing and may be involved in regulation of hematopoiesis

SEPT6 encodes four transcript variants encoding three distinct isoforms

It is allosterically activated by ADP and inhibited by GTP and ATP

Tuberin(Phospho Ser939) Polyclonal Antibody, 50ul Bottle-Top Dispenser This gene is part ofMutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.