LOXL4 Rabbit Polyclonal Antibody, 100ul Cell Culture stabilizes p53/TP53 by affecting its

stabilizes p53/TP53 by affecting its interaction with ubiquitin ligase MDM2 (PubMed: 25732823)

and breast cancer

The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule

and exists as four alternatively spliced isoforms

LOXL4 Rabbit Polyclonal Antibody, 100ul Cell Culture stabilizes p53/TP53 by affecting itsThis gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue encoding an extracellular copper dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C terminus end appears to be sufficient for amine oxidase activity suggesting that each family member may retain