Caspase 2 Rabbit Polyclonal Antibody, 20ul[BT-AP06906] ROS/Nitric Oxide Detection Mutations in this gene result

Mutations in this gene result in sporadic and familial Paget disease of bone

May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins

small ubiquitin-like modifier 2 is involved in a variety of cellular processes

This gene encodes the integrin alpha M chain

Caspase 2 Rabbit Polyclonal Antibody, 20ul[BT-AP06906] ROS/Nitric Oxide Detection Mutations in this gene resultalternative products: Isoforms differ in the N and C termini Catalytic activity: Strict requirement for an Asp residue at P1 with 316 asp being essential for proteolytic activity and has a preferred cleavage sequence of Val Asp Val Ala Asp . Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.