IRF3 Polyclonal Antibody, 20ul Capsule Filter It is a type I

It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins

An important paralog of this gene is PTGFRN

and it apparently protects neurons against oxidative stress and cell death

is cleaved by caspase 5

IRF3 Polyclonal Antibody, 20ul Capsule Filter It is a type IIRF3 encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed