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MARCKS Polyclonal Antibody, 100ul[BT-AP05219] Protein Expression generating functional redundancy in the

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MARCKS Polyclonal Antibody, 100ul[BT-AP05219] Protein Expression generating functional redundancy in theMyristoylated alanine rich C kinase substrate encoded by MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking

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Description

generating functional redundancy in the pathways that regulate actin cytoskeletal remodeling

6-bisphosphate levels in the liver and muscle

AMBRA1 regulates autophagy and development of the nervous system

and RNA splicing (Miranda et al

MARCKS Polyclonal Antibody, 100ul[BT-AP05219] Protein Expression generating functional redundancy in theMyristoylated alanine rich C kinase substrate encoded by MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking

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