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Lck(Phospho Ser540) Polyclonal Antibody, 50ul Rotator Individuals homozygous for a mutation

SKU: 78975478346

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Lck(Phospho Ser540) Polyclonal Antibody, 50ul Rotator Individuals homozygous for a mutationThis gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T cells. It contains N terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein protein interactions with phosphotyrosine containing and proline rich motifs, respectively. The protein localizes to the plasma

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Description

Individuals homozygous for a mutation in this gene are at higher risk for type 2 diabetes and have higher levels of circulating glucose and insulin levels after glucose ingestion

Mutations in NR3C are associated with generalized glucocorticoid resistance

tissue specificity:Highly expressed in placenta

The protein is a potential tumor suppressor and is involved in the pathophysiology of several tumors

Lck(Phospho Ser540) Polyclonal Antibody, 50ul Rotator Individuals homozygous for a mutationThis gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T cells. It contains N terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein protein interactions with phosphotyrosine containing and proline rich motifs, respectively. The protein localizes to the plasma

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