Rat Tumor Necrosis Factor Α, TNF-A ELISA Kit, 96T Low retention tips URI1 may play a role

URI1 may play a role in multiple malignancies including ovarian cancer and hepatocellular carcinoma

The chromosomal location of this gene to 10q24 suggests it as a candidate gene for partial epilepsy

Several transcript variants encoding different isoforms have been described for this gene

|Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage

Rat Tumor Necrosis Factor Α, TNF-A ELISA Kit, 96T Low retention tips URI1 may play a roleCytokine that binds to TNFRSF1A TNFR1 and TNFRSF1B TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin 1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via