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DFFB Polyclonal Antibody, 20ul[BT-AP08457] Funnels Mutations in this gene are

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DFFB Polyclonal Antibody, 20ul[BT-AP08457] Funnels Mutations in this gene areApoptosis is a cell death process that removes toxic and or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40 kD (DFFB) and 45 kD (DFFA) subunits. DFFA is the substrate for caspase 3 and triggers DNA fragmentation during apoptosis. DFF

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Description

Mutations in this gene are associated with hypochromic microcytic anemia with iron overload

It is not currently known whether the encoded protein is a functional ribosomal protein or whether it has evolved a function that is independent of the ribosome

is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis

The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al

DFFB Polyclonal Antibody, 20ul[BT-AP08457] Funnels Mutations in this gene areApoptosis is a cell death process that removes toxic and or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40 kD (DFFB) and 45 kD (DFFA) subunits. DFFA is the substrate for caspase 3 and triggers DNA fragmentation during apoptosis. DFF

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