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TRADD Polyclonal Antibody, 50ul Organelle Studies This gene encodes a PHOX

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TRADD Polyclonal Antibody, 50ul Organelle Studies This gene encodes a PHOXTumor necrosis factor receptor type 1 associated DEATH domain protein encoded by TRADD is a death domain containing adaptor molecule that interacts with TNFRSF1A TNFR1 and mediates programmed cell death signaling and NF kappaB activation. Tumor necrosis factor receptor type 1 associated DEATH domain protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor of apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated

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Description

This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family

This receptor binds insulin-like growth factor with a high affinity

and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module

Genomic sequences representing several pseudogenes have been described and two transcript variants encoding different isoforms have been identified for this gene

TRADD Polyclonal Antibody, 50ul Organelle Studies This gene encodes a PHOXTumor necrosis factor receptor type 1 associated DEATH domain protein encoded by TRADD is a death domain containing adaptor molecule that interacts with TNFRSF1A TNFR1 and mediates programmed cell death signaling and NF kappaB activation. Tumor necrosis factor receptor type 1 associated DEATH domain protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor of apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated

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