RNF24 Rabbit Polyclonal Antibody, 20ul Sampling Tubes Alternative splicing generates multiple transcript

Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing

Multiple transcript variants encoding different isoforms have been characterized for this gene

Knockout mice lacking this gene show that it is required for retinal cone bipolar cell differentiation| and that it negatively regulates potassium channel gene expression in the heart to ensure coordinated cardiac repolarization

Defects in this gene or the SMN1 gene can cause spinal muscular atrophy

RNF24 Rabbit Polyclonal Antibody, 20ul Sampling Tubes Alternative splicing generates multiple transcript