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ALDH3A2 Monoclonal Antibody, 50ul Vortex Mixer Alternative splicing of this gene

SKU: 78000961818

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ALDH3A2 Monoclonal Antibody, 50ul Vortex Mixer Alternative splicing of this geneAldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This gene product catalyzes the oxidation of long chain aliphatic aldehydes to fatty acid. Mutations in the gene cause Sjogren Larsson syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Description

Alternative splicing of this gene generates two transcript variants diverging in the 3' region

The protein encoded by PTPRC (protein tyrosine phosphatase

and CDK8 that can negatively regulate transactivation by mediator

The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9

ALDH3A2 Monoclonal Antibody, 50ul Vortex Mixer Alternative splicing of this geneAldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This gene product catalyzes the oxidation of long chain aliphatic aldehydes to fatty acid. Mutations in the gene cause Sjogren Larsson syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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