IP3R-I Polyclonal Antibody, 100ul[BT-AP04603] Dry Bath found changes in pathology and

found changes in pathology and behavior suggesting that the encoded protein may promote amyloid plaque formation (PMID: 19548013)

This intronless gene TSSK6 (testis specific serine kinase 6) encodes a member of the CAMK (calcium/calmodulin-dependent) serine/threonine protein kinase family

Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent

Expressed predominantly in the brain

IP3R-I Polyclonal Antibody, 100ul[BT-AP04603] Dry Bath found changes in pathology andITPR1 (inositol 1,4,5 trisphosphate receptor type 1) encodes an intracellular receptor for inositol 1,4,5 trisphosphate. Upon stimulation by inositol 1,4,5 trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in ITPR1 cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for ITPR1.