GPR143 Polyclonal Antibody, 50ul Protein Post-translational Modification The product of this gene

The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells

SEPT7 encodes septin-7 that is highly similar to the CDC10 protein of Saccharomyces cerevisiae

Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity

and clathrin

GPR143 Polyclonal Antibody, 50ul Protein Post-translational Modification The product of this geneGPR143 encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. This protein is thought to be involved in intracellular signal transduction mechanisms. Mutations in GPR143 cause ocular albinism type 1, also referred to as Nettleship Falls type ocular albinism, a severe visual disorder. A related pseudogene has been identified on chromosome Y.