DGCR8 Rabbit Polyclonal Antibody, 100ul Adeno-associated Virus Packaging This gene is one of

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17

The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al

Inhibition of the encoded protein can lead to apoptosis

The encoded protein associates with CD40| tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs)| and inhibits nuclear factor-kappa-B activation

DGCR8 Rabbit Polyclonal Antibody, 100ul Adeno-associated Virus Packaging This gene is one ofThis gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double stranded RNA binding protein that functions as the non catalytic subunit of the microprocessor complex. This protein is required for binding the double stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein Drosha. Alternate splicing results in