Rat Glypican 1, GPC1 ELISA Kit, 96T Human Genome Knockout Libraries Mediates axon repulsion of neuronal

Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding

The protein is composed of a nuclear localization domain

calcium metabolism

The protein encoded by this gene contains a classical signature of the insulin superfamily and is significantly similar to relaxin and relaxin-like factor

Rat Glypican 1, GPC1 ELISA Kit, 96T Human Genome Knockout Libraries Mediates axon repulsion of neuronalCell surface proteoglycan that bears heparan sulfate. May act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. Required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF