CENPP Polyclonal Antibody, 100ul Subcellular Fractions Ubiquitin-like modifier-activating enzyme 1 encoded

Ubiquitin-like modifier-activating enzyme 1 encoded by UBA1 catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation

and can bind RNA

An important paralog of RABEP2 is RABEP1

This gene has been found fused to a variety of translocation partner genes in various leukemias| most notably the t(9

CENPP Polyclonal Antibody, 100ul Subcellular Fractions Ubiquitin-like modifier-activating enzyme 1 encodedCENPP is a subunit of a CENPH (MIM 605607) CENPI (MIM 300065) associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006