ASPM Polyclonal Antibody, 20ul Sample Library Tubes This gene is a member

This gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain| a DHR-2 (CZH-2) domain and an SH3 domain

This protein also regulates the production of other cytokines

SIKE interacts with IKK-epsilon (IKBKE

The encoded protein has been described as a "dual-functional" deglutamylase that can remove glutamate residues from both carboxyl termini and side chains of protein substrates

ASPM Polyclonal Antibody, 20ul Sample Library Tubes This gene is a memberThis gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts. Studies in mouse also suggest a role of this gene in mitotic spindle regulation, with a preferential role in regulating neurogenesis. Mutations in this gene are associated with microcephaly primary type 5. Multiple transcript variants encoding different isoforms have been found