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JIP-3 Polyclonal Antibody, 50ul Custom RNA Oligos eIF4A unwinds RNA secondary structures

SKU: 75694281513

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JIP-3 Polyclonal Antibody, 50ul Custom RNA Oligos eIF4A unwinds RNA secondary structuresC Jun amino terminal kinase interacting protein 3 encoded by MAPK8IP3 shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart

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Description

eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit

It contains multiple binding sites for dynamin and thus links dynamin to actin regulatory proteins

Among its related pathways are PLK1 signaling events

which belongs to the SMC gene family

JIP-3 Polyclonal Antibody, 50ul Custom RNA Oligos eIF4A unwinds RNA secondary structuresC Jun amino terminal kinase interacting protein 3 encoded by MAPK8IP3 shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart

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