Beclin-1 mouse Monoclonal Antibody(5C2), 100ul Peripheral Blood Separation Tube This family member is a

This family member is a Golgi-bound member of the secretory pathway that is involved in the repositioning of lysosomes and the activation of macropinocytosis

q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma

Three members of this gene family have been studied in detail and are estimated to generate over 3000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member

Contains 2 SAM (sterile alpha motif) domains

Beclin-1 mouse Monoclonal Antibody(5C2), 100ul Peripheral Blood Separation Tube This family member is aThis gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol 3 kinase (PI3K) complex which mediates vesicle trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.