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NAL12 Rabbit Polyclonal Antibody, 20ul Adeno-associated Virus Packaging in de novo pyrimidine biosynthesis

SKU: 75561607238

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NAL12 Rabbit Polyclonal Antibody, 20ul Adeno-associated Virus Packaging in de novo pyrimidine biosynthesisThis gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein which contains an N terminal pyrin domain a NACHT domain a NACHT associated domain and a C terminus leucine rich repeat region functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple

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Description

in de novo pyrimidine biosynthesis

The protein encoded by this gene is a Rab-GTPase-activating protein| and contains two phopshotyrosine-binding domains (PTB1 and PTB2)| a calmodulin-binding domain (CBD)| a Rab-GTPase domain| and multiple AKT phosphomotifs

Has a role in chromosome translocation

A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity

NAL12 Rabbit Polyclonal Antibody, 20ul Adeno-associated Virus Packaging in de novo pyrimidine biosynthesisThis gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein which contains an N terminal pyrin domain a NACHT domain a NACHT associated domain and a C terminus leucine rich repeat region functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple

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