DSG4 Polyclonal Antibody, 20ul Centrifuge Tube (Bottle) but the biological validity of

but the biological validity of only two has been determined

This gene belongs to the family of reticulon encoding genes

First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB)

The encoded protein functions as a homodimer and interacts directly with both CSTF1 and CSTF2 in the CSTF complex

DSG4 Polyclonal Antibody, 20ul Centrifuge Tube (Bottle) but the biological validity ofThis gene encodes a member of the desmoglein subgroup of desmosomal cadherins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a transmembrane component of desmosomes and may play a role in cell cell adhesion in epithelial cells. Mutations in the gene are associated with localized autosomal recessive hypotrichosis and monilethrix, characterized by impaired hair growth.