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DCLK1 Rabbit Polyclonal Antibody, 100ul Erlenmeyer Flasks Defects in EIF2B4 are a

SKU: 75289985482

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SEK123.75 SEK168.75

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DCLK1 Rabbit Polyclonal Antibody, 100ul Erlenmeyer Flasks Defects in EIF2B4 are aThis gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N terminal doublecortin domains which bind microtubules and regulate microtubule polymerization a C terminal serine threonine protein kinase domain which shows substantial homology to Ca2+ calmodulin dependent protein kinase and a serine proline rich domain in between the doublecortin and the protein kinase domains

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Description

Defects in EIF2B4 are a cause of leukoencephalopathy with vanishing white matter (VWM) and ovarioleukodystrophy

such as cardiac rhythm and circulation

The promoter of this gene is frequently hypermethylated in these cancer tissues| although the hypermethylation does not appear to be the cause of the reduced expression of this gene

it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer

DCLK1 Rabbit Polyclonal Antibody, 100ul Erlenmeyer Flasks Defects in EIF2B4 are aThis gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N terminal doublecortin domains which bind microtubules and regulate microtubule polymerization a C terminal serine threonine protein kinase domain which shows substantial homology to Ca2+ calmodulin dependent protein kinase and a serine proline rich domain in between the doublecortin and the protein kinase domains

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