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ANR11 Rabbit Polyclonal Antibody, 100ul Variant Libraries This complex is located at

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ANR11 Rabbit Polyclonal Antibody, 100ul Variant Libraries This complex is located atThis locus encodes an ankryin repeat domain containing protein. The encoded protein inhibits ligand dependent activation of transcription. Mutations in this gene have been associated with KBG syndrome which is characterized by macrodontia distinctive craniofacial features short stature skeletal anomalies global developmental delay seizures and intellectual disability. Alternatively spliced transcript variants have been described. Related pseudogenes

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Description

This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion

The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE

Multiple transcript variants encoding different isoforms have been found for PHKG1

Cathepsin L1 encoded by CTSL1 is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism

ANR11 Rabbit Polyclonal Antibody, 100ul Variant Libraries This complex is located atThis locus encodes an ankryin repeat domain containing protein. The encoded protein inhibits ligand dependent activation of transcription. Mutations in this gene have been associated with KBG syndrome which is characterized by macrodontia distinctive craniofacial features short stature skeletal anomalies global developmental delay seizures and intellectual disability. Alternatively spliced transcript variants have been described. Related pseudogenes

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