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Ku-70 Polyclonal Antibody, 50ul[BT-AP04893] Serum & Sample Tubes The protein encoded by the

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Ku-70 Polyclonal Antibody, 50ul[BT-AP04893] Serum & Sample Tubes The protein encoded by theThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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Description

The protein encoded by the orthologous gene in rat is localized to the Golgi complex and can redistribute to microtubules

lymph node and thymus

This gene has been linked to non-small cell lung cancer

The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus

Ku-70 Polyclonal Antibody, 50ul[BT-AP04893] Serum & Sample Tubes The protein encoded by theThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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