DOLK Rabbit Polyclonal Antibody, 50ul Liquid Storage Consumables PDK1 itself can autophosphorylate Ser-241

PDK1 itself can autophosphorylate Ser-241

mouse studies link its function to adenylyl cyclase inhibition

Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2

contains seven transmembrane domains

DOLK Rabbit Polyclonal Antibody, 50ul Liquid Storage Consumables PDK1 itself can autophosphorylate Ser-241The protein encoded by this gene catalyzes the CTP mediated phosphorylation of dolichol and is involved in the synthesis of Dol P Man which is an essential glycosyl carrier lipid for C and O mannosylation N and O linked glycosylation of proteins and for the biosynthesis of glycosyl phosphatidylinositol anchors in endoplasmic reticulum. Mutations in this gene are associated with dolichol kinase deficiency.