Clock Monoclonal Antibody, 100ul Vortex Mixer Mutation or amplification of REL

Mutation or amplification of REL is associated with B-cell lymphomas

pancreatic and leukemia

The Mediator complex interacts with DNA-binding gene-specific transcription factors to modulate transcription by RNA polymerase II

only one of them protein-coding

Clock Monoclonal Antibody, 100ul Vortex Mixer Mutation or amplification of RELThe protein encoded by this gene plays a central role in the regulation of circadian rhythms. The protein encodes a transcription factor of the basic helix loop helix (bHLH) family and contains DNA binding histone acetyltransferase activity. The encoded protein forms a heterodimer with ARNTL (BMAL1) that binds E box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes.