SMG9 Polyclonal Antibody, 20ul CellSafe™ Overexpression of CDCA7 is found

Overexpression of CDCA7 is found to enhance the transformation of lymphoblastoid cells

It is required for maximal stimulated calcium release after stimulation of purinergic or muscarinic but not beta-adrenergic receptors

The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal

This gene encodes a basic helix-loop-helix transcription factor belonging to the PAS (PER

SMG9 Polyclonal Antibody, 20ul CellSafe™ Overexpression of CDCA7 is foundThis gene encodes a regulatory subunit of the SMG1 complex, which plays a critical role in nonsense mediated mRNA decay (NMD). Binding of the encoded protein to the SMG1 complex kinase scaffold protein results in the inhibition of its kinase activity. Mutations in this gene cause a multiple congenital anomaly syndrome in human patients, characterized by brain malformation, congenital heart disease and other features.