Gab 2 Polyclonal Antibody, 100ul[BT-AP03409] Mechanical Pipette Expression of this gene is

Expression of this gene is downregulated by interleukin 3 (IL3)

A similar protein in rat is thought to function in the endosomal pathway between early endosomes and mature lysosomes

suggesting a role in the regulation of DNA replication

which are known to play an important role in the formation of spliceosomes

Gab 2 Polyclonal Antibody, 100ul[BT-AP03409] Mechanical Pipette Expression of this gene isGAB2 is a member of the GRB2 associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T and B cell antigen receptors. GRB2 associated binding protein 2 encoded by GAB2 is the principal activator of phosphatidylinositol 3