Rb Polyclonal Antibody, 100ul[BT-AP07690] Microplate Mixer This isozyme is predominantly expressed

This isozyme is predominantly expressed in the gastrointestinal tract (also in liver in human)| is localized in the cytoplasm| and whose preferred substrate is hydrogen peroxide

The protein localizes to cytoplasmic filaments

The encoded protein is active in bulk vitamin C transport involving epithelial surfaces

making it ideal for labs looking to increase throughput and save time

Rb Polyclonal Antibody, 100ul[BT-AP07690] Microplate Mixer This isozyme is predominantly expressedThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.