Raf-1 Polyclonal Antibody, 50ul[BT-AP13534] Cell Function Analysis via NF-kappa-B

via NF-kappa-B

The protein has broad-spectrum antimicrobial activity against bacteria and fungi

Deficiencies in this gene can result in male pseudohermaphroditism

NF-kappa-B inhibitor alpha interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses

Raf-1 Polyclonal Antibody, 50ul[BT-AP13534] Cell Function Analysis via NF-kappa-BThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.