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Human Homeodomain-interacting Protein Kinase 2, HIPK2 ELISA Kit, 96T Enzyme-Linked Immunosorbent Assay (ELISA) The encoded protein may form

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Human Homeodomain-interacting Protein Kinase 2, HIPK2 ELISA Kit, 96T Enzyme-Linked Immunosorbent Assay (ELISA) The encoded protein may formSerine threonine protein kinase involved in transcription regulation, p53 TP53 mediated cellular apoptosis and regulation of the cell cycle. Acts as a corepressor of several transcription factors, including SMAD1 and POU4F1 Brn3a and probably NK homeodomain transcription factors. Phosphorylates PDX1, ATF1, PML, p53 TP53, CREB1, CTBP1, CBX4, RUNX1, EP300, CTNNB1, HMGA1 and ZBTB4. Inhibits cell growth and promotes apoptosis through the activation of p53

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Description

The encoded protein may form a component of several different histone acetyltransferase complexes

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Mutations in this gene result in persistent Mullerian duct syndrome

Diseases associated with ZNF608 include renal cell carcinoma

Human Homeodomain-interacting Protein Kinase 2, HIPK2 ELISA Kit, 96T Enzyme-Linked Immunosorbent Assay (ELISA) The encoded protein may formSerine threonine protein kinase involved in transcription regulation, p53 TP53 mediated cellular apoptosis and regulation of the cell cycle. Acts as a corepressor of several transcription factors, including SMAD1 and POU4F1 Brn3a and probably NK homeodomain transcription factors. Phosphorylates PDX1, ATF1, PML, p53 TP53, CREB1, CTBP1, CBX4, RUNX1, EP300, CTNNB1, HMGA1 and ZBTB4. Inhibits cell growth and promotes apoptosis through the activation of p53

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